Corrigendum to “Nk6, a novel Drosophila homeobox gene regulated by vnd” [Mech. Dev. 116 (2002) 105–116]
نویسندگان
چکیده
Corrigendum to “Nk6, a novel Drosophila homeobox gene regulated by vnd” [Mech. Dev. 116 (2002) 105–116] Jay Uhler, James Garbern, Li Yang, John Kamholz, Dervla M. Mellerick* Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA Department of Neurology, Wayne State University School of Medicine, Detroit, MI 48201, USA Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA Karmanos Cancer Institute, Detroit, MI, USA
منابع مشابه
Nk6, a novel Drosophila homeobox gene regulated by vnd
Nk(x)-type homeobox genes are an evolutionarily conserved family that regulate diverse developmental processes. Here we describe a novel Drosophila gene, Nk6, which encodes an Nk-type transcription factor most homologous to vertebrate Nkx6.1 and Nkx6.2. The homeodomains and NK decapeptide domains of all three proteins are highly conserved. Nk6 is expressed in the embryonic brain, ventral nerve ...
متن کاملEms and Nkx6 are central regulators in dorsoventral patterning of the Drosophila brain.
In central nervous system development, the identity of neural stem cells (neuroblasts) critically depends on the precise spatial patterning of the neuroectoderm in the dorsoventral (DV) axis. Here, we uncover a novel gene regulatory network underlying DV patterning in the Drosophila brain, and show that the cephalic gap gene empty spiracles (ems) and the Nk6 homeobox gene (Nkx6) encode key regu...
متن کاملContextual interactions determine whether the Drosophila homeodomain protein, Vnd, acts as a repressor or activator
At the molecular level, members of the NKx2.2 family of transcription factors establish neural compartment boundaries by repressing the expression of homeobox genes specific for adjacent domains [Muhr et al. (2001) Cell, 104, 861-873; Weiss et al. (1998) Genes Dev., 12, 3591-3602]. The Drosophila homologue, vnd, interacts genetically with the high-mobility group protein, Dichaete, in a manner s...
متن کاملRegulated vnd expression is required for both neural and glial specification in Drosophila.
The Drosophila embryonic CNS arises from the neuroectoderm, which is divided along the dorsal-ventral axis into two halves by specialized mesectodermal cells at the ventral midline. The neuroectoderm is in turn divided into three longitudinal stripes--ventral, intermediate, and lateral. The ventral nervous system defective, or vnd, homeobox gene is expressed from cellularization throughout earl...
متن کاملCorrigendum to “The dynamic expression pattern of B lymphocyte induced maturation protein-1 (Blimp-1) during mouse embryonic development” [Mech. Dev. 117 (2002) 305–309]
Corrigendum to “The dynamic expression pattern of B lymphocyte induced maturation protein-1 (Blimp-1) during mouse embryonic development” [Mech. Dev. 117 (2002) 305–309] David H. Chang, Kathryn L. Calame* Department of Microbiology, College of Physicians and Surgeons, Columbia University, 701 W. 168th Street, New York, NY 10032, USA Department of Biochemistry and Molecular Biophysics, College o...
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ورودعنوان ژورنال:
- Mechanisms of Development
دوره 119 شماره
صفحات -
تاریخ انتشار 2002